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At risk of a torrid third straight defeat in all tournaments, Chelsea welcome Manchester United to Stamford Bridge for Saturday's enticing lunchtime kickoff in the Premier League.
Xabi Alonso oversaw the Blues' exit from the EFL Cup on Wednesday evening, as the West London giants lost to Liverpool on penalties following a 1-1 draw in the fourth round.
Chelsea's elimination succeeded a dismal 2-0 reverse at home to London rivals Tottenham Hotspur, forcing the Blues out of the top five of the Premier League table.
Here, Sports Mole rounds up Chelsea's latest injury and suspension news before the visit of Man United, who remain under the wing of Michael Carrick for their trip south.
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Maxence Lacroix came off holding his hamstring just before the break against Liverpool, and while the severity of his problem has not yet been ascertained, there is little chance of him making the cut this weekend.
Status: Minor doubt
Type of injury: Unspecified
Possible return date: October 31 (vs. Man United)
Moises Caicedo was replaced in the 68th minute of Wednesday's game due to a "little problem", albeit not one that should jeopardise his involvement against the Red Devils.
Status: Minor doubt
Type of injury: Cramp
Possible return date: October 31 (vs. Man United)
Malo Gusto was also forced off midway through the second half at Anfield due to cramp, but the right-back should recover in time for the weekend.
Status: Out
Type of injury: Thigh
Possible return date: November 21 (vs. Leeds United)
Joao Pedro will be missing for a "few weeks" with a thigh injury, meaning that the Brazilian is unlikely to return to action before the November international break.
Status: Out
Type of injury: Face
Possible return date: November 21 (vs. Leeds)
Emiliano Martinez is on the mend from jaw surgery following a sickening collision with Everton's Jarrad Branthwaite earlier this month, but the Argentine should be back in between the sticks in a few weeks' time.
Status: Out
Type of injury: Knee
Possible return date: January 3 (vs. Newcastle United)
The luckless Reece James recently underwent an operation on a knee injury, and the Englishman is not expected to play again in 2026.
Status: Out
Type of injury: Ankle
Possible return date: November 8 (vs. Sunderland)
Jamie Gittens picked up an ankle injury with England's Under-21s during the last international break, and it will be a "few weeks" before he is back in contention too.
Status: Major doubt
Type of injury: Unknown
Possible return date: October 31 (vs. Man United)
Pep Chavarria has missed Chelsea's last three games with an unspecified injury, but he is stepping up his workload in training and might be back in contention on Saturday.
After seeing red for two bookable offences against Tottenham, Cole Palmer served his one-game ban in midweek, so Chelsea have no players suspended for the weekend.