Enzo Fernandez's post-match interview is going viral for the wrong reasons after Argentina lost to Uruguay in their first match since the retirement of Lionel Messi.

Manchester City midfielder Fernandez, who is the Premier League's most expensive footballer, started and played 90 minutes in what was a relatively new-look Argentina XI.

But Lionel Scaloni's side conceded two second-half goals, with centre-back Leonardo Balerdi netting an own goal before Sporting winger Maximiliano Araujo made it 2-0. Argentina pulled a goal back on 73 minutes through Julian Alvarez but it wasn't enough.

Fernandez was put up for post-match media duty and his remarks about Uruguay haven't gone down well.

Enzo Fernandez addresses Argentina's first post-Messi defeat

Speaking to reporters inside Estadio Alberto J. Armando, Fernandez said he thought Argentina dominated and controlled the game, and deserved to win. Scaloni's side had 72 per cent possession, and had 17 shots on goal compared to Uruguay's six over the course of the contest.

He then claimed that Argentina only lost the game because Uruguay scored 'two goals by chance' - a remark which has received backlash on social media.

Uruguay's first goal came after a flick-on was inadvertently headed into his own net by Balerdi; it started from a free kick which Argentina, of course, gave away.

Their second goal was from a corner, with Araujo's looping header going over the head of Rulli and into the back of the net. Prior to that, former Liverpool striker Darwin Nunez had ran through on goal after outmuscling Balerdi before forcing a fine low save from Rulli.

There were moments prior to the two goals, therefore, that could have prevented them had Argentina taken different decisions - and fans told Fernandez of that fact with their reactions.

Fans react to Enzo Fernandez's Argentina interview

Taking to Twitter to respond to Fernandez's interview, one fan wrote: "The arrogance and lack of humility are back."

"Sure, those two goals were lucky, but it's also true that Uruguay beat a mediocre team," a second said.

"What kind of generic response is that?! Sounds terrible," a third wrote.

"The same way Nottingham Forest scored three random goals?" another asked, referencing Manchester City's 3-1 defeat to Nottingham Forest at the City Ground, which took place on the Saturday before the international break.

"Last time I checked football is won when one team puts more goals in the back of the net than the other," a fifth stated.

Argentina's international break concludes with another home friendly, this time against Costa Rica. Scaloni experimented with a relatively young starting XI - at least compared to the World Cup squad - when Argentina took on Uruguay, with Thiago Almada, Nico Paz and Exequiel Palacios all handed starts. There were substitute appearances for 22-year-old Palmeiras defender Augustin Giay, Benfica's 20-year-old Gianluca Prestianni and Zenit's 22-year-old Roman Vega.