Manchester United travel to Como on Wednesday, 21 October 2026, needing a result to halt a six-match winless run and ease growing pressure on manager Michael Carrick.

The 20-time English champions have collected three points from their opening two Champions League matches, leaving them 13th in the league phase. Como are one place above them in 12th with the same total.

Como are appearing in the league phase for the first time after securing an impressive fourth-place finish in Serie A last season. Cesc Fabregas’ side made an excellent European debut on 10 September, beating RB Leipzig 4-1, but lost 3-2 away to Feyenoord Rotterdam in their next match.

The Italian club go into the game fifth in Serie A, having taken 14 points from seven matches. They beat Fiorentina 3-1 at the weekend and are the 12th Italian club to feature in Europe’s most prestigious competition.

Wednesday’s match will also be the first time Como have faced an English side. Their remaining league-phase fixtures include matches against Lens, AEK Athens, Real Betis, Paris Saint-Germain and FC Barcelona.

Manchester United began their European campaign with a 4-0 victory over Sabah before losing 2-0 at Atletico de Madrid last week. Domestically, they were held to a disappointing 1-1 draw by Leeds United, a result which leaves them 13th in the Premier League with seven points from seven games.

United have not won any of their past six matches in all competitions, drawing three and losing three. However, their record against Italian opposition remains strong, with only two defeats in their past 16 meetings, alongside 10 victories.

Como have injury doubts over Trevoh Chalobah, who has a muscle problem, and Moise Kean, who has a tibia issue. Assane Diao is ruled out with a thigh injury. Anastasios Douvikas has scored five goals in nine appearances this season and is expected to lead the attack, with Martin Baturina and Nico Paz likely to provide creativity. Jacobo Ramon is expected to start in central defence.

United will be without Manuel Ugarte, who has a knee injury, Patrick Dorgu, who has a hamstring problem, suspended defender Leny Yoro and Benjamin Sesko, who is recovering from a tibia injury. Ayden Heaven is ill, while Kobbie Mainoo, Luke Shaw and Lisandro Martinez are doubts with thigh problems.

Martinez was substituted at half-time against Leeds because of a muscular issue. Bryan Mbeumo could again operate as the central striker, while Noussair Mazraoui may replace Yoro.

Probable teams

Como: Butez; Couto, Chalobah, Ramon, Valle; Milla, Da Cunha; J. Rodriguez, Paz, Baturina; Douvikas.

Manchester United: Lammens; Mazraoui, Maguire, Martinez, Dalot; Santos, Baleba; Amad, Tielemans, Fernandes; Mbeumo.

The suggested prediction is a narrow 2-1 Manchester United win, with the exact-score selection priced at 9.00 with Betclic. Other listed options are more than 2.5 goals at 1.50, both teams to score at 1.50 and a Manchester United win at 2.80.