There will be two big clashes, as Chelsea host Manchester United and Arsenal travel to Liverpool.

Also, Manchester City will welcome Brighton for the second time this week and Tottenham take on Crystal Palace in a London derby.

Shearer, speaking to Betfair, said: "Chelsea vs Manchester United: Prediction – Chelsea win.

"Manchester City vs Brighton: Prediction – Manchester City win."

"Tottenham vs Crystal Palace: Prediction – Tottenham win."

"Aston Villa vs Fulham: Prediction – Aston Villa win."

"Liverpool vs Arsenal: Prediction – Draw."