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On target for Mullion in their 3-2 victory were Harry Blatch, Harry Luckett and Jonny Wheatley.
Leaders Penryn Athletic were 3-0 winners away to Penzance Reserves, with Reece Carroll giving Athletic the lead after 13 minutes.
A goal from Josh Wood and a goal two minutes from time secured victory.
League champions Pendeen Rovers had a convincing 5-0 victory away to Illogan RBL, where Ben Chapman (2), Alex Ralph (2) and Will Garner were the goalscorers.
Redruth United moved up into third place after winning 5-3 at home to St Just.
Perranwell won a tight game 3-2 at home to St Day.
Joe Crossman and James Petty had Saints’ goals.
Porthleven won their sixth successive game when they defeated Wendron United 3-2 with goals from Charlie Young, Dexter Bainbridge and Nick Barber.
Ludgvan’s 7-1 win against Camborne SoM enabled them to exchange places in the league table with the home side, scoring through Ross Duncan (2), Josh Findlay (2), Jordan Richards, Jack Willis and an own goal.
Perranporth dropped their first points in division one (West) after they were held to a 1-1 draw at Porthleven Reserves where Kai Delaney netted for Port.
Newlyn Non-Athletico picked up all three points from their 4-0 win at Wendron United III.
Division two (West) leaders Mawgan raced to a 5-1 win away to Perranporth Reserves after notching goals through Harry Price (2), Stan Burtenshaw, Owen Fairclough and Josh Travis.
Falmouth DC won 1-0 at St Agnes Reserves after scoring the only goal of the game through Josh Salter.
There was an amazing scoreline at Dropship Reserves who were beaten 17-0 by Holman SC Reserves.
A local derby in division three (West) saw Penryn Athletic Reserves defeat Tremough 4-3.
Tremough scored through Dexter Evans, George Allen and Bardhyl Nushi.
Daniel Hopkins scored for Ludgvan Reserves in their 6-1 defeat at Troon.
A hat-trick from Chris Shackley and a goal from Jason Holt earned Chacewater a 5-3 win against Stithians.
Goals from Louis Brown (2), David Mitchell, Tre Arnold and Sam Bullen set up Goonhavern Reserves’ 5-2 win against RNAS Culdrose Reserves.
Jacob Thornhill and an own goal enabled St Keverne to win 2-0 at Newlyn Non-Athletico Reserves.
Falmouth Athletic held division four (West) league leaders Carharrack to a 3-3 draw after netting through Hayden Phillips, Jordan Lawry and Adam Laker.
The visitors replied through Cal Pearson, Dylan Tiddy and Jordan Tiddy.
St Agnes III, who scored through Sam Luckett, Oliver Deacon, Maxim Cornish and an own goal, moved off the foot of the table with a 4-3 win against Lizard Argyle Reserves.
Redruth United Reserves are right on the tails of the leaders following their 3-1 win at St Day Reserves.
Speak Out United went down 11-1 at Trelawny where Gracious Gariba scored the goal.
The top match in the George Evely Cup saw Holman SC defeat Mawnan 7-6 on penalties after the game had ended 1-1 after extra time.
Harry McMellon scored for Mawnan and Callum Faulkner levelled five minutes from time.
Falmouth United were 4-1 winners at Lizard Argyle where they scored through a George Harry hat-trick and a goal from Archie Becconsall.
Mullion Reserves were beaten 7-4 at home by RNAS Culdrose after scoring through Ewan Lea (2), Andy Bowden and Charlie Bennett.
West Cornwall defeated Pendeen Rovers 4-0.
Extra time was needed for Probus to defeat St Buryan 3-2 with goals from George Orrell, Connor Rhodes and Fred Hocking.
Ashley Ellis had both Saints’ goals.
Hayle Reserves were 5-2 winners at St Just Reserves where Will Matthews and Jeff Robinson scored for the home side.
Lanner pulled off a huge upset when they defeated unbeaten Helston OBs 4-3 in the Cornwall Junior Cup with the goals coming from Dave Mitchell (2), Sam Charlton and Aidan Tovey.