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Wade had zero points (0-2 FG, 0-2 3Pt), two assists and one steal over 13 minutes in Friday's 125-120 preseason loss to the Celtics.
Wade suffered an ankle injury in the first half, Kyle Neubeck of AllPHLY.com reports. Head coach Nick Nurse wasn't overly concerned but chose to keep him off the floor for the remainder of the contest. The 29-year-old, who signed with the 76ers in the offseason, should at least be considered questionable ahead of the Opening Night meeting with the Knicks. If Wade can't suit up, Anfernee Simons and Dominick Barlow would presumably each receive a few more minutes.