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The Tigers made a flying start and opened the scoring inside three minutes after a patient build-up deep inside the visitors’ 22 allowed centre Joe Bedlow to cross beneath the posts.
Oli Glasse converted.
Sedgley doubled their advantage 12 minutes later when prop Beltus Nonleh powered through three tackles to score, with Glasse again adding the extras.
Debutant winger Freddie Ferguson then marked his first Tigers appearance with a try in the corner as the hosts moved 19-0 ahead.
Fylde responded through winger Leo Gilliand, who crossed twice in eight minutes to reduce the deficit to 19-10 and bring the visitors back into contention.
However, Tigers finished the half strongly.
Bedlow spun out of two tackles to score his second and secure the bonus point before Glasse converted.
There was still time for another score before the interval as Nonleh made the initial break and flanker Alex Minozzi supported well to cross for Sedgley’s fifth try, giving them a commanding 33-10 half-time advantage.
The hosts had to wait until the 53rd minute for their next score when a penalty was kicked deep into Fylde territory.
The forwards drove towards the line and hooker Luke Cole touched down.
Fylde responded through hooker Robert Williamson, with Daniel Slawson converting, but Sedgley quickly reasserted their authority.
Prop Danny Rylance powered over from close range and Glasse’s conversion stretched the advantage to 45-17.
Fylde continued to battle and centre Aaron Pope, playing opposite his brother Nathan, broke through midfield to score near the posts.
Replacement hooker Adam Mallinson added Sedgley’s eighth try after reacting quickly to take a penalty close to the Fylde line.
The visitors refused to give up, however, and Gilliand completed his hat-trick with a well-worked fifth Fylde try.
Sedgley closed out a 52-27 victory to collect another five-point haul and preserve their unbeaten record.
Two-try centre Bedlow was named man of the match by the visitors, while Nonleh earned the star player award from Buzze Sports.
Sedgley now face a tough trip to fourth-placed Hull Ionians next Saturday.