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Fighting to avoid a drop into the Premier League's relegation zone, Manchester United will welcome Aston Villa to Old Trafford on Sunday.
Michael Carrick's job may have been saved by a dramatic 3-2 win over Roma in the Champions League on Tuesday, while Unai Emery is closing in on a new contract despite losing 3-0 to Barcelona in midweek.
Here, Sports Mole rounds up all of the latest team news for both clubs.
Out: Lisandro Martinez (suspended), Carlos Baleba (hamstring), Marcus Rashford (hip), Benjamin Sesko (shin), Luke Shaw (undisclosed), Manuel Ugarte (ACL)
Doubtful: Patrick Dorgu (hamstring)
Sports Mole's predicted XI: Lammens; Yoro, Maguire, Heaven, Dalot; Tielemans, Mainoo; Diallo, Fernandes, Mbeumo; Cunha
Out: Matty Cash (suspended), Matteo Ruggeri (hamstring), Amadou Onana (ACL)
Doubtful: Aaron Wan-Bissaka (hamstring)
Sports Mole's predicted XI: Suzuki; Bogarde, Torres, Lindelof, Maatsen; Goretzka, Kamara; Alysson, McGinn, Manzambi; Jackson