CLEVELAND — The Cavaliers are bracing for another encounter with Akron native LeBron James and the Philadelphia 76ers, this time at Rocket Arena.

The Cavs opened their 2026-27 season on Oct. 22 by blowing a 29-point lead on the road and losing 114-106 to the Sixers.

Now the Cavs (4-4) hope to avoid falling below .500 in James' first game in Cleveland as a member of the 76ers (8-1). After spending the past eight seasons with the Los Angeles Lakers, James announced on July 24 he would sign with the 76ers in free agency instead of his other primary suitors, the Cavs, Miami Heat, Golden State Warriors and Minnesota Timberwolves.

Cavaliers starting lineup vs. 76ers

76ers starting lineup vs. Cavs

• Point guard Tyrese Maxey

• Guard VJ Edgecombe

• Forward Jaylen Brown

• Forward LeBron James

• Center Joel Embiid

Cleveland Cavs injury report vs 76ers

The Cavs listed starting center Jarrett Allen (right knee contusion), starting wing Peyton Watson (right hamstring injury management) and guard Tyrese Proctor (left ankle sprain) as questionable to play. They also ruled out the following players:

• Wing Jaylon Tyson (right ankle sprain)

• Forward Nae'Qwan Tomlin (low back stress reaction)

• Center Khalifa Diop (NBA G League — on assignment)

• Center Ernest Udeh, Jr. (NBA G League — two-way contract)

76ers injury report vs. Cavaliers

The Sixers listed center Adem Bona as doubtful (cervical spine sprain) to play. They also ruled out the following players:

• Forward Dominick Barlow (low back stress reaction)

• Center Ariel Hukporti (right Achilles tendon rupture/tear)

The Cavs have an all-time record of 115-120 against the 76ers in the regular season.

Cleveland and Philly have gotten off to contrasting starts this season. The Cavs were 3-1 before losing three of their past four games, including the last two.

The 76ers won five consecutive games and boasted the NBA's best record entering games played on Nov. 6.

Will the Cleveland Cavs and Philadelphia 76ers meet again this season?

The Cavs and Sixers are slated to play once more during the 2026-27 regular season. Cleveland will host Philadelphia at 7 p.m. March 1.

Where to watch Cavaliers vs. 76ers tonight on TV

Cavs versus 76ers will be televised by Prime Video.

How can I listen to Cavs vs 76ers tonight on radio?

The local radio broadcast of the Cavs-76ers game can be heard via WTAM (1100-AM), WMMS (100.7-FM) or La Mega Cleveland (Spanish broadcast, 1300-AM).