While the Houston Texans are banged up in several spots entering Week 6, the Jacksonville Jaguars took a significant hit ahead of their matchup across the pond Sunday morning.

Jaguars left tackle Anton Harrison plans to undergo arthroscopic surgery on his right knee when the team returns from London next week, meaning he'll be out for the matchup against Houston. The team doesn't yet know the severity of the injury that was suffered in Sunday's 19-17 victory over Philadelphia, though it is expected that the former first-round pick with either miss three to five weeks or the remainder of the regular season.

Harrison was placed on the injured reserve Tuesday. He had been the best offensive lineman for Jacksonville during the five weeks dating back to Week 1. Former second-round pick Walker Little is expected to start in his place.

Harrison, the 27th overall pick in 2023, was moved from right tackle to left tackle during training camp. He had missed just three games at right tackle in his first three seasons.

Houston's defensive line has been lethal against quarterbacks this season. Entering Sunday's showdown at Wembley Stadium, the Texans are tied for second in sacks wth 17, including seven by All-Pro defensive end Will Anderson Jr.