Manchester United’s 1-1 draw against Leeds United extended their winless run to six matches across all competitions.

The result followed a 2-0 defeat to Atletico Madrid in Europe, leaving Carrick searching for a response on the continental stage.

Their next opponents, Como, will be hoping to make home advantage count as Cesc Fabregas prepares his side for the visit of the Premier League club.

With both teams coming into the fixture after demanding spells of football, squad availability could have a significant influence on Wednesday’s contest.

12 players to miss Como vs Manchester United game

Manchester United and Como both have fitness questions to address before their Champions League meeting, with United monitoring several players while Fabregas waits for clarity on defenders Yan Couto and Trevoh Chalobah following Sunday’s match against Fiorentina.

Lisandro Martinez is one of the latest concerns after being withdrawn at half-time against Leeds.

Carrick confirmed the substitution was due to a thigh issue, and the defender’s fitness will need to be assessed before United travel to Como.

His availability matters given the defensive changes United have already had to navigate in recent weeks.

Both missed the away fixture against Leeds, and their availability has been uncertain.

Shaw’s absence has created further questions at left-back, while Mainoo’s situation limits Carrick’s midfield options if he remains unavailable.

Benjamin Sesko is still working through a shin problem, with Carrick previously explaining that the striker was undergoing further checks before a clearer return timeline could be provided.

Patrick Dorgu remains a concern after sustaining a hamstring injury while on international duty with Denmark, while Manuel Ugarte is recovering from knee surgery after being injured during the summer.

Veteran goalkeeper Tom Heaton has also been sidelined with a hamstring issue.

There is one definite disciplinary issue for Wednesday as Leny Yoro is suspended after being sent off against Atletico Madrid.

That is not an injury, but it removes another defensive option from Carrick’s selection choices.

Como have their own problems following the 1-1 draw with Fiorentina.

Couto was due to start but withdrew after experiencing discomfort during the warm-up, with Smolcic taking his place.

Chalobah then had to come off early in the match, with Jacobo Ramon replacing him.

The club had not confirmed the full extent of either issue, so it remains too early to say whether either defender will miss the United game.

Como have also been monitoring attacking options.

Assane Diao suffered a hamstring injury after scoring against Feyenoord in the Champions League.

Moise Kean has also been managing a shin problem, although Italian reporting indicated he could return for the meeting with United.

With United desperate to end their winless run, the trip to Como offers Carrick a chance to change the narrative.