Aston Villa midfielder Johan Manzambi has been ruled out of Switzerland's Nations League matches against Slovenia and Scotland.

The Swiss FA has revealed that the 21-year-old, who went off after 78 minutes of Sunday's 4-4 Premier League draw with Manchester United, had arrived at the national team's training camp on Monday already suffering from a calf issue.

"Despite intensive medical care and further assessment, his condition has not improved sufficiently, making it impossible for him to feature in either match," it states.

"In consultation with Aston Villa, Manzambi will return to his club this Friday."

Switzerland, who lead Group B1 by five points, are already without captain Granit Xhaka after the veteran midfielder picked up an injury playing for Sunderland at the weekend.

However, they have decided not to call up a replacement before facing second-top Slovenia in Maribor on Friday.

Murat Yakin's side need just a point to finish top of the section and secure promotion to League A before concluding their group campaign at home to Scotland on Monday.