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Manchester United host Aston Villa at Old Trafford in a huge Super Sunday Premier League clash on November 8, live on Sky Sports.
Man Utd are struggling in 17th place in the Premier League table and could find themselves in the relegation zone come kick-off should earlier results go against them over the weekend.
United do though enter the fixture off the back of a 3-2 comeback win against Roma in the Champions League in midweek.
Aston Villa enter the weekend 10th in the table and are on a five-game unbeaten run in the Premier League, but suffered a heavy defeat to Barcelona in midweek.
In the two league meetings between the sides last season, Aston Villa won 2-1 at Villa Park before Man Utd won 3-1 at Old Trafford in March.
Manchester United vs Aston Villa in the Premier League takes place on Sunday November 8 at Old Trafford. Kick-off is 4.30pm UK and Ireland time.
TV: Sky Customers can watch on Sky Sports Main Event and Premier League from 4pm
App: Sky Customers can also watch on the Sky Sports app
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Online: Anyone on the move can follow live coverage of the game through our dedicated match blog
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Sky Sports' Lewis Jones...
Unai Emery clearly sees something special in Johan Manzambi, handing him a prominent role at Aston Villa and the early signs suggest he could make a serious splash this season.
The numbers are already eye-catching. Manzambi has delivered a goal or assist every 81 minutes in the Premier League this season. Backing him to score or assist has landed in all six league games he has started (including super sub concession). That's a pretty compelling return for a player still finding his feet at this level.
His developing partnership with Nicolas Jackson is particularly exciting. There's a nice understanding emerging between the pair, while Manzambi's wider numbers suggest this isn't simply a purple patch. He averaged a goal involvement every other game for club and country last season.
And the scary thing for opponents? He's only going to get better.
Manchester United are going to struggle to contain him. They are without a clean sheet in nine Premier League games this season and remain a side struggling for consistency and control.
At 13/8 with Sky Bet, Manzambi to score or assist looks a lovely price.
Carlos Baleba has been ruled out for several weeks with the hamstring injury suffered against Roma in midweek.
Patrick Dorgu is being assessed after returning to training. Marcus Rashford, Benjamin Sesko, Luke Shaw and Manuel Ugarte remain absent.
Lisandro Martinez is suspended following his red card against Chelsea last weekend.
Matty Cash is suspended for Aston Villa after picking up his fifth booking of the season last time out.
Fellow full-back Aaron Wan-Bissaka faces a late fitness test after being sidelined for the last few weeks, while Matteo Ruggeri and Amadou Onana remain absent through injury.