49ers rookie defensive tackle Gracen Halton’s fourth-quarter injury didn’t look good at the time, and unfortunately, it was as bad as it looked.

Coach Kyle Shanahan said postgame that Halton broke his left ankle, ending Halton’s season.

Medical personnel placed a vacuum splint on Halton’s left leg with 3:57 remaining on an interception by 49ers safety Malik Mustapha. Halton was carted to the X-ray room.

The fourth-round pick had no stats Sunday. He will finish his season with 15 tackles, two sacks and a forced fumble.

It is the latest defensive line injury for the 49ers, who already have Alfred Collins, Andrew Farmer II, C.J. West, Mikail Kamara and Sam Okuayinonu on injured reserve at the position. Nick Bosa played Sunday for the first time since Week 3 when he injured his calf, and he totaled a tackle for loss.