Brian Flores is known for producing some of the best defenses in football, and on Monday Night Football, the Buffalo Bills and quarterback Josh Allen will face a Minnesota Vikings stop unit that ranks first in EPA per play and pressure rate.

Allen knows the Vikings' defensive coordinator very well from when he faced the Miami Dolphins from 2019 to 2021, when Flores was their head coach. If past results are any indication, Allen should have no problems picking up where he left off.

The Bills were 6-0 against the Dolphins in those three seasons, and they won those games by an average margin of about 18 points. Given how weak the Vikings' offense is (28th in EPA per play), Allen and Co. may not need to do much to reach that threshold.

How has Josh Allen fared vs. Brian Flores' defenses?

Allen had yet to break out as a superstar in the league when he began facing Flores, and in his six games against him, he completed 64.4% of his passes for 1,525 yards and a 16-2 touchdown-to-interception ratio. He added 200 yards and two more scores on the ground in those contests.

These stats do not account for Allen sitting the entire second half of Buffalo's meaningless Week 17 contest against Miami in 2020, so these stats technically span five and a half games.

Though Allen has had success against Flores in the past, there is plenty more talent for the defensive wizard to work with in Minnesota to try to befuddle Allen than he ever had in Miami.

Flores in Miami vs. Flores in Minnesota

Outside linebacker Andrew Van Ginkel is one player Allen will know well from his matchups against the Dolphins. He's a do-it-all defender for Flores, as he leads the Vikings with 6.5 sacks and 8.5 tackles for loss. In the four games he played under Flores against Allen, he registered 13 tackles, two sacks and a forced fumble.

Flores did not have another elite edge defender in Miami, but Dallas Turner, with six sacks and 8.5 TFLs, is blossoming in his third season as that piece. Both Van Ginkel and Turner rank in the top 10 in the NFL in sacks.

In the linebacking core, veteran Blake Cashman is another chess piece for Flores to use, as he leads the Vikings with 64 tackles and also has 4.5 sacks and five passes defensed.

Cornerback Xavien Howard was the only All-Pro Flores had in Miami, but Isaiah Rodgers, Byron Murphy and James Pierre have combined for six of the Vikings' eight interceptions this season, forming a trio that is hard to complete passes against.

Safety Joshua Metellus is another versatile piece, as he often plays in the box or in the slot to shut down opposing playmakers.

Despite such a talented group of defenders, Allen has a couple of advantages he'll need to emphasize if the Bills are to win their seventh game of the season.

Keys to victory

#Skol #Vikings DC Brian Flores on #BillsMafia QB Josh Allen:

"Josh is one of the best players in our league."

Allen enters MNF with 20 total TD so far this season for the 6-1 Bills. pic.twitter.com/K6owGJUpvT

— Will Hall (@WillHallKARE11) November 3, 2026

The Vikings blitz on 72.8% of defensive plays, by far the most in the NFL by about 30 percentage points. They also lead the league with an 11% sack rate. Fortunately for Buffalo, Allen doesn't take a nosedive against pressure. In fact, he's one of the league's better quarterbacks against extra rushers.

Allen has an overall rate of 0.22 EPA per play, fourth-best among quarterbacks with at least 100 snaps. His 0.11 EPA per play against the blitz is 10th in the league and -0.03 EPA per play against pressure is third-best.

For reference, the seven quarterbacks Minnesota has faced so far have combined for 0.15 EPA per play against the blitz and -2.72 EPA per play against pressure.

Allen can also lean on James Cook and the running game to settle down the pass rush and keep it honest. Jahmyr Gibbs ran for 153 yards and a touchdown on 23 carries against Minnesota on Sunday, so Cook having a similar performance will help massively.

Going against Flores' defense is a tough task for any quarterback, but if anyone can overcome it, Allen can.